Cell Therapy Operations Associate, Hoofddorp, Noord-Holland

The Company   The client is a leading player in the specialized nutrition industry, dedicated to improving the well-being of vulnerable groups, including infants, the elderly, and individuals with medical conditions. With a strong focus on innovation, quality, and compliance, our client works closely with co-manufacturers to ensure that all products meet the highest standards of safety, regulatory requirements, and nutritional excellence.   Role Description As a Process Engineer, you will play a key role in improving the reliability, efficiency, and performance of liquid manufacturing processes for specialized medical nutrition and infant nutrition products distributed worldwide. Working closely with production teams, you will support operational excellence by addressing process deviations, leading root cause investigations, and implementing sustainable improvements that reduce recurring issues and minimize reactive firefighting. You will act as a technical expert within the production environment, collaborating with operators, team leaders, quality specialists, and project teams to ensure production processes consistently meet safety, quality, and operational standards. In addition, you will contribute to strategic improvement initiatives and may assume selected departmental responsibilities in the absence of the department manager. Responsibilities Drive improvements in process reliability, quality performance, operational efficiency, and safety within the production area. Monitor and analyze production performance, working closely with operators and production teams on the shop floor. Coach and support production personnel in accurately documenting process disturbances, downtime, and operational deviations. Identify improvement opportunities based on production data and lead initiatives to enhance process stability and performance. Lead root cause analyses for major incidents impacting key operational KPIs and establish effective preventive actions. Troubleshoot process-related issues and provide timely technical support to maintain production continuity. Represent the department in cross-functional projects, including the implementation of new processes and technologies. Ensure production and quality requirements are incorporated into project designs, testing, and verification activities. Collaborate with operators and production team leaders to resolve operational challenges and optimize workflows. Support business continuity by taking on selected departmental responsibilities when required. Requirements Bachelor's or Master's degree in Food Technology, Mechanical Engineering, Process Engineering, or a related technical discipline. Minimum 1-3 years of experience within a manufacturing or production environment. Experience within food, pharmaceutical, medical device, or other highly regulated industries is preferred. Demonstrated experience in continuous improvement methodologies and process optimization. Experience working in multidisciplinary project teams and managing improvement projects. Strong analytical and problem-solving skills with proven experience in root cause analysis. Ability to work effectively in a dynamic production environment and manage time-sensitive operational challenges. Strong communication and stakeholder management skills. Results-oriented, proactive, and solution-driven mindset. Excellent reporting, documentation, and data analysis capabilities. Strong project management skills with a structured and detail-oriented approach. Flexible and capable of providing practical solutions to operational and process-related issues. Fluent in Dutch (mandatory) with a good command of English. Other information   Apply to our vacancy for more information. Looking forward to getting in touch!  

Company: Our client is a leading international organization in the life sciences sector, focused on delivering high-quality products to patients worldwide. The site in Breda plays a key role in supply chain execution, product readiness, and cross-functional collaboration to support launches and ongoing product lifecycle activities. Role summary: We are looking for a Supply Chain Manager to lead and coordinate end-to-end supply chain execution for product launches, variations, and ongoing lifecycle activities at site level. The role combines project management, cross-functional stakeholder alignment, and operational discipline to ensure changes are implemented compliantly, on time, and with clear visibility across the organization. Key responsibilities: •    Translate launch and lifecycle strategies into clear supply chain objectives, action plans, and timelines for assigned product groups. •    Own and maintain the end-to-end project plan, aligning inputs from regional and site stakeholders. •    Lead and manage the Change Control process to ensure launch and variation activities are delivered right first time and in line with internal procedures and guidance. •    Track milestones, manage dependencies, and drive adherence to agreed timelines; escalate risks and issues as needed. •    Facilitate Product Lifecycle Team meetings and lead project management meetings with relevant functions. •    Coordinate planning and implementation across key stakeholders including Quality, Regulatory, Production and Site Planning, Artwork, Warehouse, Customer Service, and Procurement. •    Provide status updates, reports, and metrics on launch execution, variation implementation, and site readiness. •    Identify opportunities to streamline ways of working and lead improvement initiatives, embedding best practices across stakeholders. •    Support regional leads and senior stakeholders with project charters, workshops, and structured project delivery. Requirements: •    Degree-level education (Bachelor’s or higher) or equivalent experience. •    Proven project management experience within supply chain, operations, or a related environment. •    Strong analytical and problem-solving skills with the ability to manage complex, cross-functional work. •    Strong stakeholder management and communication skills. •    Pharmaceutical industry experience preferred. Other information: This is a hybrid position with one mandatory on-site day per week in Breda (Tuesdays). If you are interested and want to apply, please submit your application via the apply button below and contact me.

The Company A leading international manufacturer in the food and nutrition industry, producing specialized liquid nutritional products for infants, elderly people, and patients. The organization operates a highly regulated production environment with a strong focus on quality, safety, innovation, and continuous improvement while supplying products to markets worldwide. About the Role As a Process Engineer, you will play a key role in improving process reliability, production efficiency, and product quality within a liquid manufacturing environment. You will be responsible for troubleshooting production issues, leading root cause investigations, and implementing sustainable improvement initiatives. Working closely with operators and production teams, you will drive operational excellence and support long term process optimization. Responsibilities - Improve safety, quality, operational performance, and equipment reliability - Support production teams in documenting process disruptions and downtime - Analyze production deviations and identify root causes of incidents - Lead investigations and define corrective and preventive actions - Initiate and manage continuous improvement projects - Collaborate closely with operators and production team leaders on the manufacturing floor - Participate in projects involving new processes and production technologies - Ensure production and quality requirements are met during process implementation and validation - Monitor and improve unit KPIs through data driven analysis - Support departmental activities and management tasks when required Requirements - BSc or MSc degree in Food Technology, Mechanical Engineering, Process Engineering, or a related discipline - 1 to 3 years of experience in a manufacturing environment - Experience within food, pharmaceutical, medical, or related regulated industries is preferred - Proven experience in continuous improvement methodologies - Strong root cause analysis and problem solving skills - Experience working in multidisciplinary project teams - Strong analytical and reporting capabilities - Excellent communication and stakeholder management skills - Ability to work effectively in a dynamic production environment with changing priorities - Strong project management and organizational skills - Fluent Dutch language skills are essential - Good command of the English language Other Information If you are interested and want to apply, please submit your application via the apply button below and contact me.

Company Our client is an international manufacturing company known for operating within a highly regulated production environment. Using advanced automated manufacturing and packaging technologies, the organisation is committed to delivering high-quality products while maintaining the highest standards of safety, compliance, and operational excellence. Continuous improvement, teamwork, and innovation are key drivers of success across the site. Job Description We are currently seeking an Automated Production Line Technician (GMP) to join a dynamic production team. In this position, you will be responsible for ensuring automated production lines operate efficiently, safely, and in accordance with GMP guidelines. You will play an important role in maintaining equipment performance, resolving technical issues, and supporting production continuity through proactive problem-solving and process optimisation. Key Responsibilities - Work with automated production and packaging equipment in accordance with GMP requirements and standard operating procedures. - Prepare production lines for operation by carrying out equipment set-ups, product changeovers, cleaning activities, and line clearance procedures. - Investigate and resolve equipment faults and process disruptions to minimise production downtime. - Fine-tune machine settings and process parameters to improve productivity, efficiency, and product quality. - Register and verify production information using SAP, MES, and related manufacturing systems. - Complete production documentation accurately, including batch records, equipment logs, and operational documentation. - Assist with deviation investigations and support root cause analysis using structured troubleshooting methodologies. - Collaborate with Production, Maintenance, and Quality teams to resolve technical issues and restore production performance. - Drive continuous improvement initiatives by applying Lean principles and identifying opportunities to optimise manufacturing processes. - Promote a safe working environment while ensuring effective communication during shift handovers. Requirement - Technical education at MBO level or an equivalent qualification such as VAPRO B. - Previous experience within automated production, assembly, packaging, or process manufacturing. - Strong technical aptitude with proven troubleshooting and analytical problem-solving skills. - Familiarity with structured improvement methodologies including Root Cause Analysis (RCA), 5 Why, Lean, or Kaizen. - Experience working within GMP or another regulated manufacturing environment is highly desirable. - Knowledge of SAP, Manufacturing Execution Systems (MES), or comparable production software. - Good communication skills in English. - Flexible to work rotating 3-shift and 5-shift schedules. - Available for a temporary full-time assignment via SIRE Life Sciences. Why Apply? This opportunity is ideal for someone who enjoys working with advanced manufacturing technology and takes pride in improving production performance. You'll become part of an environment where technical expertise, teamwork, and continuous improvement are valued every day. If you're looking for your next challenge in automated manufacturing, we'd love to hear from you. Apply today by clicking the application button below or contact me directly for more information.

Company Our client is an international pharmaceutical and biotechnology organization with a modern manufacturing facility in Breda. The site combines advanced production technology with strict GMP, quality, and safety standards. To support growing production activities, we are looking for several hands-on professionals who enjoy working with machinery, solving technical problems, and improving production processes.   Job Description As a Automated production Line technician, you will help ensure that manufacturing and packaging equipment performs reliably throughout the production process. You will prepare equipment for production, respond to operational issues, complete required documentation, and contribute to maintaining a safe and efficient manufacturing environment.   Responsibilities - Keep manufacturing and packaging equipment running efficiently throughout production. - Prepare machines for different production runs, including set-ups, changeovers, line clearance, and shutdown activities. - Identify equipment or process issues and carry out first-line troubleshooting. - Perform minor machine adjustments to restore or improve equipment performance. - Complete GMP and production documentation accurately and on time. - Carry out required equipment and production-area cleaning activities. - Follow established GMP, SOP, quality, and safety procedures. - Identify recurring production issues and contribute to reducing downtime and improving efficiency. - Escalate complex technical problems to the appropriate technical specialists. - Collaborate with production, quality, and technical teams to maintain smooth operations. Requirements - MBO-level education or equivalent technical/production experience. - Previous hands-on experience within manufacturing, production, packaging, or process operations. - Experience working with automated or semi-automated production equipment. - Knowledge of GMP, SOPs, or regulated manufacturing procedures. - Experience completing GMP or production documentation. - Familiarity with machine set-ups, changeovers, line clearance, and close-down activities. - Experience performing cleaning activities within a production environment. - Good technical troubleshooting skills and confidence making minor equipment adjustments. - Good communication skills in English. - Willingness to work within a rotating shift schedule. Interested? If you enjoy hands-on technical work, modern production technology, and problem-solving, we would like to hear from you.  

Company Our client is a well-established organisation in a highly regulated manufacturing environment, operating a complex site with critical utilities and electrical infrastructure. Safety, compliance, and reliable day-to-day operations are key priorities, alongside continuous improvement and investment in site projects. Job Description We are looking for an Electrical Operations & Project Engineer to support safe, compliant electrical operations on site and to lead/contribute to improvement and capital projects. This is a hands-on engineering role focused on practical application in the field—ensuring electrical work is planned and executed safely, systems remain reliable, and projects are delivered in line with Dutch regulations and site standards. Responsibilities - Act as the on-site electrical subject matter expert supporting daily operations and maintenance activities. - Ensure electrical installations are inspected, maintained, modified, and operated in line with NEN 3140 (and NEN 1010 where applicable) and internal EHS/engineering standards. - Provide hands-on troubleshooting support, including root cause analysis for electrical failures and operational issues. - Oversee safe execution of electrical work, including permit-to-work processes, lockout/tagout (LOTO), and contractor activities. - Support audits, inspections, and compliance activities, ensuring documentation and electrical dossiers are accurate and up to date. - Support the electrical scope of site projects from early concept through commissioning and handover to operations. - Review and approve electrical designs, specifications, calculations, and drawings to ensure they meet standards and site requirements. - Coordinate with internal stakeholders, contractors, and engineering partners to deliver work safely, on time, and within agreed parameters. - Participate in risk assessments, safety reviews, and HAZOP-style discussions related to electrical systems. - Identify and drive improvements in reliability, maintainability, and energy efficiency of electrical systems. Requirements - BSc or MSc in Engineering (mandatory). - NEN 3140 certification (mandatory); NEN 1010 preferred. - Minimum 5 years’ relevant experience (ideal 5–10 years). - Strong low-voltage electrical experience with proven hands-on site/field capability. - Experience supporting both operations/maintenance and projects (small to medium projects and improvements). - Background in pharmaceutical, industrial, or other regulated manufacturing environments is strongly preferred. - Able to work effectively on-site; English is sufficient (Dutch not required). Other Information Site presence is important, with flexibility for limited home working after onboarding. If you are interested and want to apply, please submit your application via the apply button below and contact me.  

Company   Our client is a modern manufacturing site in Breda, operating in a highly regulated environment with a strong focus on quality, safety, and continuous improvement. The organisation uses advanced, highly automated production systems and works to strict procedures to ensure consistently high standards. Role Description   We are looking for an Automated Manufacturing Technical Operator (GMP) to run and optimise automated production lines. This role combines hands-on operation with technical troubleshooting, accurate documentation, and a continuous improvement mindset to support safe, efficient, and compliant manufacturing. Responsibilities   - Operate and monitor automated production equipment in line with SOPs and GMP requirements - Perform set-up and close-down activities to keep production running smoothly - Troubleshoot technical issues and carry out root cause analysis to prevent recurrence - Adjust mechanical and parameter settings to optimise performance and minimise downtime - Collect, record, and verify production data in SAP/MES systems - Complete GMP documentation accurately and on time (e.g., batch records, logs) - Analyse process performance, identify deviations, and escalate where needed - Take part in cross-functional triage discussions with Quality, Maintenance/Engineering, and Production - Support continuous improvement initiatives using Lean and structured problem-solving methods - Ensure clear shift handovers and effective communication within the team - Work safely at all times and contribute to a compliant, well-organised shopfloor environment Requirements   - At least 3 years’ experience in a similar production/operator role, ideally in assembly and packaging - Proven experience working with automated production lines (pharma or food industry preferred) - Technical education such as MBO / VAPRO B (or equivalent) - Strong understanding of GMP and working to SOPs in a structured environment - Confident using SAP/MES or similar production/ERP systems - Strong troubleshooting skills and familiarity with methods such as 5 Why, RCA, Kaizen, TPM, SMED, Fishbone - Technical knowledge in areas such as mechatronics, pneumatics, and/or electronics - Fluent in English - Willing to commute to Breda and work a shift system   Other Information If you are interested and want to apply, please submit your application via the apply button below and contact me.  

Company A leading organisation in the life sciences sector, committed to maintaining high standards of safety, quality, and operational reliability. The company values innovation and continuous improvement, providing a dynamic environment for professionals dedicated to engineering excellence. Role Description We are seeking an experienced Senior Electrical Engineer to join our client's team, supporting electrical operations and leading key projects to ensure system integrity and compliance. The role includes maintaining electrical safety standards while contributing to the successful delivery of capital and maintenance projects across the site. Responsibilities - Serve as the electrical expert for daily site operations, ensuring all electrical systems are operated, maintained, and modified safely and in compliance with Dutch regulations (including NEN 3140 and NEN 1010), internal standards, and EHS policies. - Assist in troubleshooting, root cause analysis, and resolving electrical failures or deviations in operational processes. - Manage electrical work permits, Lockout/Tagout procedures, and contractor activities to uphold safety standards. - Support and oversee electrical aspects of capital projects, from initial design review and approval to execution and handover. - Review electrical designs, specifications, and drawings to ensure they meet engineering standards and regulatory requirements. - Coordinate with internal teams, contractors, and engineering partners during project delivery, commissioning, and system handovers. - Maintain comprehensive technical documentation, including asset registers and electrical dossiers, ensuring regulatory compliance. - Identify opportunities for improving system reliability, energy efficiency, and ease of maintenance, supporting best practice sharing across the organisation. - Participate in safety assessments, risk evaluations, and audits to ensure ongoing compliance and operational safety. Requirements - Bachelor’s degree in Electrical Engineering or related field. - Mandatory certification in NEN 3140; NEN 1010 experience is preferred. - Several years of experience working in industrial, pharmaceutical, or other regulated manufacturing environments. - Proven experience supporting both operational and capital project activities. - Strong knowledge of low-voltage and medium-voltage electrical systems. - Familiarity with managing contractors and working within regulated environments. - Fluency in English; Dutch language skills are a plus. Other Information If you are interested and want to apply, please submit your application via the apply button below and contact me.

Over het bedrijf Onze opdrachtgever is een internationale organisatie die gespecialiseerde medische voeding en babyvoeding produceert voor kwetsbare doelgroepen. Vanuit de Supply Point in Zoetermeer worden vloeibare producten geproduceerd en naar meer dan 55 landen gedistribueerd. Functieomschrijving Als Proces Engineer Vloeistofverwerking draag je actief bij aan de betrouwbaarheid en optimalisatie van het productieproces. Je werkt nauw samen met operators en productieteamleiders op de werkvloer om procesafwijkingen op te lossen en structurele verbeteringen te realiseren. Je voert root cause analyses uit, ontwikkelt oplossingen voor terugkerende problemen en neemt deel aan of geeft leiding aan verbeterprojecten. Daarnaast vertegenwoordig je productie binnen projecten rondom nieuwe processen, kwaliteitseisen en verificatieactiviteiten. Belangrijkste verantwoordelijkheden Optimaliseren van productieprocessen met focus op veiligheid, kwaliteit, prestaties en betrouwbaarheid. Troubleshooten van procesafwijkingen en ontwikkelen van structurele oplossingen. Coachen van productieteams bij het correct documenteren van verstoringen en stilstanden. Leiden van analyses bij grote incidenten en identificeren van grondoorzaken en preventieve acties. Definiëren en uitvoeren van continu verbeterprojecten op basis van productiegegevens en geïdentificeerde problemen. Vertegenwoordigen van productie in projecten rondom nieuwe processen, productie-eisen en kwaliteit. Nauw samenwerken met operators en productieteamleiders om problemen op de werkvloer op te lossen. Samenwerken met experts uit verschillende disciplines en bijdragen aan verbeterinitiatieven. Leveren van analytische en rapportagegerichte input aan de Problem Solving Group. Ondersteunen van de afdeling en indien nodig bepaalde verantwoordelijkheden overnemen bij afwezigheid van de Department Manager. Functie-eisen Een afgeronde BSc- of MSc-opleiding in Levensmiddelentechnologie, Levensmiddelentechniek, Werktuigbouwkunde of een vergelijkbare technische richting. 2+ jaar ervaring in een productieomgeving, bij voorkeur binnen food, pharma of medical. Aantoonbare ervaring met continuous improvement en root cause analysis. Ervaring met het werken aan projecten binnen multidisciplinaire teams. Sterke analytische, probleemoplossende en rapportagevaardigheden. Je voelt je prettig in een dynamische productieomgeving en kunt onder tijdsdruk ad-hoc problemen oplossen. Sterke projectmanagementvaardigheden en een nauwkeurige, gestructureerde werkwijze. Proactief, resultaatgericht en oplossingsgericht. Goede communicatieve en samenwerkingsvaardigheden. Vloeiend Nederlands is vereist; kennis van het Engels is noodzakelijk.

Company Our client is a leading organisation within the pharmaceutical sector, focused on delivering high-quality products to patients through strong operational planning, compliant execution, and continuous improvement. The site in Breda plays a key role in supporting product launches and lifecycle activities across the region, working closely with a range of internal stakeholders. Job Description We are looking for a Supply Chain Project Manager (Product Launch & Lifecycle) to lead end-to-end planning and execution for product launches, variations, and lifecycle management activities at the site level. This role blends project management, cross-functional coordination, and operational excellence to ensure changes are delivered on time, in full compliance, and with clear visibility to stakeholders. Responsibilities - Translate launch and lifecycle strategies into clear supply chain objectives and actionable site plans for assigned product groups. - Own and maintain the end-to-end launch project plan, coordinating inputs from regional and alliance stakeholders as required. - Drive the change control process for launches, variations (including CMC and labelling), and lifecycle initiatives—ensuring “right first time” execution and milestone adherence. - Facilitate project and product lifecycle team meetings, keeping actions, timelines, and decisions moving forward. - Lead cross-functional project management meetings to support effective delivery across Quality, Regulatory, Production/Site Planning, Artwork, Warehouse, Customer Service, and Procurement. - Deliver site readiness updates, communicate risks and dependencies early, and present performance metrics for launches and variations. - Identify opportunities to streamline ways of working and lead improvement projects that enhance delivery, compliance, and efficiency. - Support development of project charters and workshops when needed to align stakeholders and scope. - Contribute to supply chain business cases and initiatives such as SKU management, rationalisation, and new packaging configuration implementation. Requirements - Degree-level education (or equivalent), with relevant professional experience. - Proven project management experience, ideally in a complex, regulated environment. - Strong problem-solving and analytical skills, with the ability to manage multiple stakeholders and timelines. - Clear communication skills and confidence presenting updates and metrics. - Preferred: experience in the pharmaceutical industry. Other Information The role is based in Breda, Netherlands, with a hybrid setup and one mandatory onsite day each Tuesday. If you are interested and want to apply, please submit your application via the apply button below and contact me.